… It occurs in individuals who produce food-specific IgE antibodies. … and thereby prevent
FcϵRI-mediated mast cell activation. … They found that two independent strains of mice lacking mast …

… of the high-affinity FcεRI on mast cells, triggering cellular … reduced allergen-specific responses
in a peanut allergy mouse … disease-modifying allergen-independent therapies available …

… to mice that express hu instead of mouse FcεRIα; mice that … ; an IgE-independent decrease
in mast cell responsiveness (… mechanisms involved in FcεRI-mediated mast cell activation and …

… marrow-derived MCs from mice that were humanized for the … mechanism against subsequent
allergen-mediated FcεRI/IgE … no amelioration of IgE-independent anaphylaxis40, 41 was …

… of the peanut allergen rather than the canonical allergen itself … promotes survival, inhibition
of Fas/FasL-independent … the FcεRI-IgE-mediated allergic signaling in human and mouse cells…

… for the Fc region of IgE (FcεRI) present on the cell surface (2). … born from mice sensitized
before pregnancy develop allergic … of littermates from three independent litters were challenged …

… anaphylaxis to peanut in a mouse model of peanut allergy (34). … with FcϵRI has been shown
to inhibit IgE-mediated mast cell … allergen-independent manner with bispecific antibodies to …

… Finally, our results demonstrated that G-ASDIS is mediated … we noticed a decrease in
spontaneous activity immediately after … The number of mast cells in the abdominal cavity of mice …

… mice could be activated by the allergen via the IgE/FcεRI … repeated allergen exposure, which
likely occurs in allergen-… sensitized mice had undergone IgE/FcεRI-mediated degranulation. …

… receptor that causes IgE-independent mast cell activation. The … In an experimental IgE-mediated
food allergy mouse model, … FcεRI-mediated signaling, resulting in the suppression of IgE-…